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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43ef1a07b7e111aa2e4b13947b3968e6a27aeca4270b7141ef956fe66dd0240' 
  AND token = 'jALNBqsxDDevdLW49t/D7IU37D85JSn1PW3mLZxiQtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}