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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91f377db16c9d6299b80c20d1e208cba5e3700f003b775c8652a45e450ed9d3a' 
  AND token = 'CP2WA23nS7bHUNLm4FsHtjbz2bgySZ+gjnw9DDGUhck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}