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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '845e5720f4032e002fd8c0757dc64badbe34b358dc48ed5d148c8a34ca5695e9' 
  AND token = 'ACd+DUblPjHDzvwC/+l9MyaL2BOG/SZ3Wix/cfx7CwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}