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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67c49bfc6af7d9897a8b09458df5f24e5ff02719be28275cd02dc22c9575cab6' 
  AND token = '1OFyK4iPVdxWZ1RQC4fv6JO4zXd7yqJh5pPAx4D5P6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}