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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7dc635ea0df486dbe44f15e83328558a7a00008741d5a3ae7590df61daa0bd' 
  AND token = 'Rt2nLvejvYu3ryoSmGxt+D7GnIBHANH/eIvifq4HcOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}