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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b21bd92d8f13bcc59db7c7debc41a9cecf9d0ceddf82d170dfb36ac436aa6a2' 
  AND token = 'EWb4cgYka12jFs+lz01CVMj9YRouWZjy11SbN2+lEOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}