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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8cb083bf3fa83831d35ccc848f6e2be8fbf7a0a33f52a477f63127dfc597d54' 
  AND token = 'c1bvEeJ9iTy/xKiOAeUOAWRH80xbSe/YwVIjBiKr5Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}