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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb49a0e167575d34dac466dcdabc13784e60e5ba20fe7c312739993826c2e89' 
  AND token = '7sUF0BMamzF6d1ZeAXJd9mTbubnLaOm3XKEG9WB2VA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}