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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f60b8b0501ca96c24e1dc4fe2253acf2cc30ef0dec094c8d38125482f9e28706' 
  AND token = 'EuRv29q49EXOrZZtpJL8LnmeXGijLLY1TXOqpZksJgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}