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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca2173d00c1e181f1ff9d9ca76c9bfb7b0274c91454448787b393f8b0dce831e' 
  AND token = 'lrE2C86FFS6D5vZyr2z3Pr1Sd2YwhdQpgUlAAEIDngc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}