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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a80a991d2915c8f05fe9db461917bdbe84c2ace6f7ff3db9780de4c357de371' 
  AND token = 'k0leF+vdAAKLTd66JYRDGlYvsPkm7UeFmZtkU3bRUAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}