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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afff80a39376ea72836621863fcc3f20becb17391764f9a5776315d7ff9035ae' 
  AND token = 'qYSsLNnqvH9DA0Kf9f2Mnfeb8ofONyrPu0zeKTw8JGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}