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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5446d6084ab6a7ed8d9b185223ff951ca6109a0c4658d08ad45cad05b912863c' 
  AND token = 'LCE7ofLeAOoCsMmbLYQepwFRY+9pDTYEvsiOp2itexE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}