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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2aae5c0f4b81a0b40d8379ca801d7243a938e7a3ed918c953d24a5197323755' 
  AND token = 'Ox3DDJVWRMs4cTU28c1WuEDlYgDtiJ3JJ+Wz09cmKl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}