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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd0164f588e0a6146e92154c3d384e94e226ab03b208e47dd17dbafab832d058' 
  AND token = 'p6/PNyRmg+tQm7yVzrGrKQnNLKZtLFC0XI3F53ml1ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}