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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8110d2b34be6ad2318c4504d821d353aa2a9c96b2d595d4da007bfc44210130' 
  AND token = 'QW1dfqIZNr6f6K2F5vQTdjedCYBS+Kq/OJmifB/CHZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}