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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2045754a802ad8d951c7db837999e4efdcc947ec2d43639dfa7bf5eb044f140' 
  AND token = 'RoQJlnnlmFYM4uPrB8v/l3QL+uYQKowllaWYXtI2p4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}