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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f20edc76ddc48e1d0a6d2503daa44850ef412faa94dfdc6369ab94e52fb1fc45' 
  AND token = 'cG/y2eoYKfmldjfVz40etiURsCLZzRsOhY8hpyJLDx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}