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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '744750763a2f710f481ca18631995f4a48bbc6f492fe142e63e32bbf7c90817d' 
  AND token = 'NOfQa9D4z1kT7GWZ1NfyccVGK/jB6MrBShfzt3so7XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}