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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5196d119c3b43512770508dbc083d1c738a926def979e204ae951c9da15561f6' 
  AND token = 'MYdT46DFz/c6FdQxhG5dM+YdBF7QKcTLQxvuoxCb+G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}