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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '348ae4a3753b7348ffc20bef3e10c3d04379ca9e43f844ad9458482c813b64b1' 
  AND token = 'xDL2uVar1yKia10f1HMWC5AsTC37x6vrOWUZ7w6Zhog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}