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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7be9ceb3cac57d8896b7353034ada50f83ba1d5777db67fae39410698dacf6' 
  AND token = 'WIr7+eN74/zU6ZHDH+vX6A87kYHAYpLWRY5G9FeFiY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}