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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19bebb1ca7ea014448c678e44369e9770c6179fb282a5d6d94743c064e45c446' 
  AND token = 'ACGmrxnD35Q7Q/HKKsdOa0XWHzo3JT3xs3QKKrAJTD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}