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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57e007d56a35be7fd402a855df705d9f6535f0437fa6995b1d53c8ff7bd653b6' 
  AND token = 'dQsFvLk+MyfMCiY1wvUO4Rjrec1sEoRpG2XS82tzKRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}