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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6ad5a9081d70b159784b18660b14e260f278ccee4090babd612581bac522ab8' 
  AND token = 'HdCbQ1hP8gjQUpp3AlC8AgJcytj4BuZQmaFofV0YHGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}