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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f378f5a6a75eb20a2e3cb84ea30d984d80aaf0704288e6a1a892fba8eba21e4' 
  AND token = 'rgC1UV5jQJKGjlx0y/rc8JTT+MRXHOdgOmsR9y5EjU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}