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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e0d13ffce037a2058c7b313f5618f4e563b91ff78b1d7d3bd699d8c9afdf7b2' 
  AND token = 'qTPuTRqDBF8Npi8E4TMDHO36a5QC3QVsCexWBcuIAFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}