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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d1826d3cdeec6bc973ce971bdec9b98f52acfa16d4673cf833c25d8dfa11313' 
  AND token = '3Foy1U0DQ8StIXkoFNkZ+uWLZYyZfxnHWyRa5GrrPrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}