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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b788370b99e66582a863cd4aeaa84046cbcaea611e5bcdcd630cd93ac3f644a' 
  AND token = 'jEPahdTptANbi8yD1Qw7Rq1rELBneP9BkR6sMN5KFwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}