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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f431cda0f954e6303fb54eb8278f33deeb25d2b64e5fb40b9bdccfd9c654cc' 
  AND token = 'Jd7o9N5r+Lt6DJuDbQ5tp3rJUYviFjF0j+I2geN/kF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}