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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '991682c9f1e4e999fd95553c3fa7177af05e99d51e941975720405215ea6db39' 
  AND token = 'Z3ak96UKiTenn/sYc2BdQIXrcwjPkM8+eR1FO1sZJQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}