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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa4c181aa75a59f93f403cb519671a9c2a982116fb7b26408671dbe345b6571a' 
  AND token = 'WY7LJvkekh79ha2msUR1x9UZ1cM75MYITa5qij5yRsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}