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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a13226cfb1b87030099b34987160f100baa182445fc992692e97446f01f45771' 
  AND token = 'a+8f9NkOLm/RbI/XZw5XgaBh5qR/O6S2USW+a3mfDLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}