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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4d2f02f7419ea5f3cf106d38e8f6c53951806bcf10d03cfa3d32f09c4f145e' 
  AND token = 'ex4dRz0M85KEwCzKnw6nygUiVaNln7uZCfINeJv4cCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}