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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e86351f61b0e23375bd744f21b6ed023a98278ef71f8993f3736275272dd216' 
  AND token = 'bKgtMm72Tnr+7+Ew6Kj0kX51Ewg7XCGWRhItwDUTYyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}