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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3453083c3e5ee3129bdc9165bfce8e4fd92e6e89ce50404f6347866d12e896f6' 
  AND token = 'M8gnKdY6w6Ck0Pxyj7CsjazKZ4GotSkMmXQ+tohmSyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}