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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d385d58d22b7f2bebc6b686b97cfa0ae8885a5a529d26c9db48551123bdffce' 
  AND token = 'lv43DXRrsCX+srzUesgHnNp/TLIQ/arvYtvKDrb0DjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}