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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5ad10a3a3401accdeef97e3fd331fc842ebc5188a2b544a5d2c697c6f3ca622' 
  AND token = 'xxxnYxJWHSH77WgE5mhmYXs2urZI4yL4tu2XNlw0sAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}