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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7580babca3e1b172566784f2820c46fdf47de453539e8d4edabca64894d0c3f' 
  AND token = '7E+sEgiwLVuY5P7WB7FiJXLyO6FRSsM8sXhY6x9ei1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}