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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6535d0befc239a704b9b35f6c01f165c7bce09f63a3d2c91cb2e5cf3723b9581' 
  AND token = '6UAAODyGIKbjiKVCprS15xlXhXTIrTMsMOUJbNjXWlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}