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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec350e4fec5e1471e672851d6324a03eb1caaa4019747d1a4f9777505e843b27' 
  AND token = 'IT+TM560iCfTngg4kTn8ZCMXALpeZsu3vAITvC9K/vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}