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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3bba21feb46750ddf4915ea38960776873906279aed2a40927cfabb457bc030' 
  AND token = 'jIcf0D86vM0fcGaC8GtOe//rLO6Jab3OT+8CZytiexs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}