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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d4a1bf2a3a017a4d79b8a5c86b16ebb53da083078c42f9004b6f8a63d39ed6' 
  AND token = 'bR5KKnpuSMlt31eOFJU6l8fv4xHbGFy69ou0/SvX0EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}