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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e443845999957d277f0789a9708a617a9ac0b3b2e0c5b300417dc62f7284820' 
  AND token = 'CAcvIdkj+c6aSGJpv3SySv6a+qu+Y8y3MJLpejRJ39g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}