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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a81f7104b4986d23f2ff35734e7e0a60bb7742852094400392df87800162c51' 
  AND token = 'Cr0g5WT1s+yYkLix3IChhE19hjn/z3y8WGRlDXvVE3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}