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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f38b5111a17fb7b0887270fb074210b071c6b82c411707e0f222ad87dbdf634' 
  AND token = 'c75cnTZRGDmgs2MuhOngc1kqZYsaq4GnD7pR7M1D0H8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}