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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24cb7169452bcf8ae063e64a3839032e3c325512b9f415fe5e415157b6985979' 
  AND token = 'kMQB9+457kmHarXjTGH+iFzh1d0oUPon9hRV48Gc2gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}