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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b33ec9c282a08afa6098c582e3565a0b4ff35230c40bf3f0fe8d9e70d131b15' 
  AND token = '1xz1eu0sCFjkjMmiorco2LEGyCsrWV9pYnCTjYgJf0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}