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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4107c7a9943c7cb3c6ad37bf53bc6634b20522465be3de5f08074404fd2d7fdb' 
  AND token = '+h2YDZ2rV4Y9w+W4ZSTXReFepVZQuoC2dFxiuVDesxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}