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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a38d04d214411e9da5608e6fe4f7c4bd0639824c70974bb83c17be832e2f1b49' 
  AND token = '8EPDOTas06E9G3+8mXMOo7xc+6hdOsJr1X0Hev5NNoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}